Probably from optanomai (through the idea of sharpness of vision); a snake, figuratively, (as a type of sly cunning) an artful malicious person, especially Satan -- serpent.
see GREEK optanomai
ὄφεις (opheis) − 3 Occurrences
ὄφεσιν (ophesin) − 1 Occurrence
ὄφεων (opheōn) − 2 Occurrences
ὄφιν (ophin) − 3 Occurrences
ὄφις (ophis) − 4 Occurrences